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Help with po300 code

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My 04 Tahoe 5.3 motor has a random multiple misfire that keeps jumping from one side to the other I have done all the regular stuff plugs wires coils ECM mass air flow sensor problem still exists any thoughts

Vehicle: 2004 Chevrolet Tahoe 5.3 motor

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The oxygen sensor, a faulty oxygen sensor can cause a random misfire event

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