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what will cause cylinder misfire

Vehicle: 2001 Oldsmobile silhouette v6

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Start by replacing spark plugs and wires, If that does not help maybe the coil is. You can try to move two coils around and see if the code changes to a different cylinder misfire.
 
Possible causes:
- Faulty spark plug 5
- Clogged or faulty fuel injector 5
- Faulty ignition coil 5
- Fuel injector 5 harness is open or shorted
- Fuel injector 5 circuit poor electrical connection
- Ignition coil 5 harness is open or shorted
- Ignition coil 5 circuit poor electrical connection
- Insufficient cylinder 5 compression
- Incorrect fuel pressure
- Intake air leak

 

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