Service engine soon light came on and hooked OBD II up an code PO443 came up
The P0443 code means that there is a problem with the EVAP Canister Purge Volume Control Solenoid Valve. Your vehicle may require to replaced the valve, but there is also a factory service bulletin that suggest that before replacing the valve you should reprogram the Engine Control Module (ECM). Unfortunately only the dealer can reprogram the ECM for your Frontier.
See "Tech notes" on the code page for a copy of the service bulletin: https://www.autocodes.com/p0443_nissan.html
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