2005 xterra 4.0L, common problem p0300

Question

p0300, starts fine, cleaned maf, no pacific cylinder misfire, hard take off lack power. exhaust spudder when take off.

Answer 1

P0300 Random misfire

When there is a random misfire event this mean there are 2 or more cylinder creating the misfire condition  Most misfire condition occur due to a ignition coil being faulty,